Uterus1.com: Great Information, Real Community, Better Living.
 Register
 Login
 Main Page
 Uterus News
Feature Story
 Education Center

Conditions
Treatments
Diagnostics

Find a Physician
HTA in the News
 Heavy Periods Center
sharonbober  Uterus
 Hero™

Dr. Sharon Bober:
Healing the Sex Lives of Cancer Patients
About Heroes
 Join the Discussion in  Our Forums
 Community
Uterus1 Forums
Patient Stories
Frequently
    Asked Questions

One Question Poll
    Archive

 Reference
Locate a Specialist
Online Resources
Uterus Anatomy
Video Library
Menstrual Diary
Office Visits
Patient Brochures
  
advertisement
Search the Body1 Network
June 18, 2019  
UTERINE NEWS: Feature Story

  • Print this Article
  • Email this Article
  • Soy May Lead to Thickening of Uterine Walls

    Soy May Lead to Thickening of Uterine Walls


    July 28, 2004

    By Rebecca Ostrom for Uterus1

    Women have been using soy to ease their menopausal symptoms for years. Evidence suggests it can also help protect against many types of cancer, including breast cancer.

    However, a new study shows a potential downside of soy supplements. Prolonged use of soy tablets may increase the risk of endometrial hyperplasia, the thickening of the uterus lining. Endometrial hyperplasia is linked with endometrial and uterine cancer.

    Italian researchers conducted a study of the effects of soy on the uterus. Nearly 400 healthy, postmenopausal women took either tablets containing 150 mg of soy isoflavones or placebos daily for a period of five years. (Only 298 of the 376 women who began the study completed the process. No explanation was given for why 78 women did not finish the study.) The researchers, led by Dr. Vittorio Unfer at the University of Perugia, analyzed uterus biopsies taken at the beginning of the study, midway through, and at the end.

    Six women who took soy supplements during the study had hyperplasia in their final biopsy, while no women who took placebos had hyperplasia at the end of the study. The positive hyperplasia rate of 3.37% is considered "statistically significant." Although hyperplasia is a risk factor for cancer, none of the biopsies showed any cancer cells in the women’s uteruses.

    Soy is a popular menopausal supplement. It is a source of phytoestrogens, which act similarly to estrogen in the body. Soy reduces symptoms such as hot flashes and loss of bone density. It is also believed to reduce the risk of estrogen-related cancers.

    The dose of isoflavones prescribed in the study was nearly twice the recommended dosage necessary to increase menopausal health. A typical dose is 80 mg or less per day.

    Previous studies have reached conflicting conclusions regarding the effect of isoflavones on the endometrium. Some have stated that phytoestrogen in soy may lead to a thickening of the uterine walls or that it will not protect a person from hyperplasia, while others have said that there is no discernable link. Other studies have found that soy extracts can prevent hyperplasia.

    The results of the five-year study were published in the July issue of Fertility and Sterility.

    Last updated: 28-Jul-04

    Comments

  • Add Comment
  •    
    Interact on Uterus1

    Discuss this topic with others.
     
    Feature Archives

    Breast Milk as Nutrition and Medication for Critically Ill Infants

    Study Finds New Moms Still Excessively Sleepy After Four Months

    Preterm Infants and Their Mothers Benefit from Maternal Singing During Skin-to-Skin Contact

    Stress Impacts Ability to Get Pregnant

    Link Discovered Between Bacteria and Premature Water Breaking

    Next 5 Features ...

    More Features ...
       
     
    Related Multimedia

    The Importance of Medical Technology In Women's Lives - by Representative RosaDeLauro (D-CT) (low bandwidth)

    Pregnancy after Fibroids Treatment

    More Features ...
     
    Related Content
    New Findings in Endometritis Study

    PMS May Predict Symptoms Later in Life

    Study Finds Doctors’ Diagnosis of Uterine Cancer Frequently Inaccurate

    Estrogen Replacement Lowers Fracture Risk

    Menopause is Affected by the Seasons

    More Features ...
     
    Home About Us Press Jobs Advertise With Us Contact Us
    advertisement
    © 2019 Body1 All rights reserved.
    Disclaimer: The information provided within this website is for educational purposes only and is not a substitute for consultation with your physician or healthcare provider. The opinions expressed herein are not necessarily those of the Owners and Sponsors of this site. By using this site you agree to indemnify, and hold the Owners and Sponsors harmless, from any disputes arising from content posted here-in.